| Edgar Abraham | Person | Male | Puerto Rico, United States | | | | | |
| Midnerély Acevedo | Person | Female | Puerto Rico, United States | 1972-02-19 | | | | |
| Natalie Albino | Person | Female | | | Puerto Rico, United States | | | |
| Nicole Albino | Person | Female | | | Puerto Rico, United States | | | |
| Alex Gárgolas | Person | Male | Puerto Rico, United States | 1971-04-24 | | | | 4 |
| Alex the Greatest | Person | Male | Puerto Rico, United States | 1983-02-20 | Puerto Rico, United States | | | |
| Alexis | Person | Male | Puerto Rico, United States | 1979-08-05 | | | | |
| Alexis & Fido | Group | | Puerto Rico, United States | 2002 | Cayey | | | 4 |
| Tite Curet Alonso | Person | Male | Puerto Rico, United States | 1926-02-26 | Guayama | 2003-08-05 | Baltimore | |
| Julito Alvarado Y Del Sur Al Norte | Group | | Puerto Rico, United States | 2000 | | | | |
| Amaro | Person | Male | Puerto Rico, United States | 1980-08-04 | | | | 4 |
| Ana Isabelle | Person | Female | Puerto Rico, United States | 1986-04-11 | Caguas | | | |
| Andy Boy | Person | Male | Puerto Rico, United States | | Carolina | | | |
| Aniel | Person | Male | Puerto Rico, United States | | | | | |
| Anuel AA | Person | Male | Puerto Rico, United States | 1992-11-27 | Carolina | | | 3.5 |
| Arcángel | Person | Male | Puerto Rico, United States | 1985-12-23 | New York, New York, United States | | | 4 |
| Arcángel & De La Ghetto | Group | | Puerto Rico, United States | | | | | 4 |
| Baby Ranks | Person | Male | Puerto Rico, United States | | Puerto Rico, United States | | | 4 |
| Baby Rasta & Gringo | Group | | Puerto Rico, United States | | | | | 4 |
| Bad Bunny | Person | Male | Puerto Rico, United States | 1994-03-10 | San Juan | | | 4.25 |
| Manolo Badrena | Person | Male | Puerto Rico, United States | 1952-03-17 | San Juan | | | |
| John Benitez | Person | Male | United States | | Puerto Rico, United States | | | |
| Obie Bermúdez | Person | Male | Puerto Rico, United States | 1980-01-10 | Aibonito | | | 5 |
| Bimbo | Person | Male | Puerto Rico, United States | | | | | |
| Blanca | Person | Female | United States | 1986-02-10 | Puerto Rico, United States | | | |
| Eddie Bobé | Person | Male | New York, New York, United States | | Puerto Rico, United States | | | |
| Sophia Burgos | Person | Female | Puerto Rico, United States | 1991 | | | | |
| Joe Caldas | Person | Male | Puerto Rico, United States | | | | | |
| Jorge Calderón | Person | Male | United States | | Puerto Rico, United States | | | |
| Tego Calderón | Person | Male | Puerto Rico, United States | 1972-02-01 | | | | 4 |
| Calle 13 | Group | | Puerto Rico, United States | 2004 | Trujillo Alto | | | 4.65 |
| Ángel Canales | Person | Male | Puerto Rico, United States | 1950-06-29 | San Juan | | | |
| Canario y su Grupo | Group | | Puerto Rico, United States | | | | | |
| Bobby Capó | Person | Male | Puerto Rico, United States | 1922-01-01 | Coamo | 1989-12-18 | New York, New York, United States | |
| Pedro Capó | Person | Male | Puerto Rico, United States | 1980-11-14 | San Juan | | | |
| Milton Cardona | Person | Male | Puerto Rico, United States | 1944-11-21 | Mayagüez | 2014-09-19 | New York, New York, United States | |
| Junior Cepeda | Person | Male | Puerto Rico, United States | 1948-11-21 | Santurce | 1974-06-29 | New York, New York, United States | |
| Chayanne | Person | Male | Puerto Rico, United States | 1968-06-28 | Las Piedras | | | 4.5 |
| Cheka | Person | Male | Puerto Rico, United States | 1983-04-05 | Brooklyn, New York, New York, United States | | | 4 |
| Coati Mundi | Person | Male | Puerto Rico, United States | 1950-01-03 | New York, New York, United States | | | 5 |
| Santos Colón | Person | Male | Puerto Rico, United States | 1922-11 | Sabana Grande | 1998-02-21 | Carolina | |
| Cortijo y su Combo | Group | | Puerto Rico, United States | 1954 | | | | 5 |
| Cosculluela | Person | Male | Puerto Rico, United States | 1980-10-15 | Humacao | | | 4 |
| Elvis Crespo | Person | Male | Puerto Rico, United States | 1971-07-30 | New York, New York, United States | | | 4 |
| Bobby Cruz | Person | Male | Puerto Rico, United States | 1937-02-01 | | | | 4.5 |
| José Miguel Cueto | Person | Male | Puerto Rico, United States | | Puerto Rico, United States | | | |
| Cultura Profética | Group | | Puerto Rico, United States | 1996-05-16 | San Juan | | | 5 |
| Daddy Yankee | Person | Male | Puerto Rico, United States | 1977-02-03 | San Juan | | | 4.15 |
| Dálmata | Person | Male | Puerto Rico, United States | 1980-02-29 | Puerto Rico, United States | | | 4 |
| Dantesco | Group | | Puerto Rico, United States | 2003 | | | | |
| Darell | Person | Male | Puerto Rico, United States | 1990-01-05 | | | | |
| Virgilio Dávila | Person | Male | Puerto Rico, United States | 1869-01-28 | | 1943-08-22 | | |
| De La Ghetto | Person | Male | Puerto Rico, United States | 1984-09-17 | | | | 5 |
| Eddie Dee | Person | Male | Puerto Rico, United States | 1977 | | | | 3 |
| Carmelo Díaz Soler | Person | Male | Puerto Rico, United States | | | | | |
| Justino Díaz | Person | Male | Puerto Rico, United States | 1940-01-29 | San Juan | | | |
| Divino | Person | Male | Puerto Rico, United States | | | | | 5 |
| DJ Goldy | Person | Male | Puerto Rico, United States | | | | | |
| Doble A & Nales "Los Presidentes" | Group | | Puerto Rico, United States | | | | | |
| Don Omar | Person | Male | Puerto Rico, United States | 1978-02-10 | San Juan | | | 4.5 |
| Dyland & Lenny | Group | | Puerto Rico, United States | | | | | 5 |
| Echo | Person | Male | Puerto Rico, United States | | | | | |
| Eliel | Person | Male | Puerto Rico, United States | 1981-01-07 | | | | 5 |
| Shawn Elliot | Person | Male | United States | 1937-03 | Puerto Rico, United States | 2016-03-11 | New York, New York, United States | 5 |
| Pablo Elvira | Person | Male | Puerto Rico, United States | 1937-09-24 | | 2000-02-05 | | |
| Escobar | Person | Male | Puerto Rico, United States | | | | | |
| Ralph Escudero | Person | Male | Puerto Rico, United States | 1898-07-16 | Manatí | 1970-04-10 | Puerto Rico, United States | |
| Fade el Que Pone la Presión | Person | Male | Puerto Rico, United States | | | | | 4 |
| Farruko | Person | Male | Puerto Rico, United States | 1991-05-02 | Bayamón | | | 4 |
| Cheo Feliciano | Person | Male | Puerto Rico, United States | 1935-07-03 | Ponce | 2014-04-17 | San Juan | 5 |
| Ruth Fernández | Person | Female | Puerto Rico, United States | 1919-05-23 | Ponce | 2012-01-09 | San Juan | |
| Fido | Person | Male | Puerto Rico, United States | 1979-07-14 | | | | |
| Pedro Flores | Person | Male | Puerto Rico, United States | 1894-03-09 | Naguabo | 1979-07-14 | San Juan | |
| Kris Floyd | Person | Male | Puerto Rico, United States | | | | | |
| Luis Fonsi | Person | Male | Puerto Rico, United States | 1978-04-15 | San Juan | | | 4 |
| Danny Fornaris | Person | Male | Puerto Rico, United States | 1984-06-16 | Las Piedras | | | |
| The Four Amigos | Group | | Puerto Rico, United States | | | | | |
| Franco “El Gorila” | Person | Male | Puerto Rico, United States | 1979-05-21 | Trujillo Alto | | | 4 |
| Gaby Music | Person | Male | Puerto Rico, United States | | | | | |
| Richie Gajate‐Garcia | Person | Male | Puerto Rico, United States | | Queens, New York, New York, United States | | | |
| Gallego | Person | Male | Puerto Rico, United States | | | | | |
| Louis Garcia | Person | Male | United States | 1905-08-25 | Puerto Rico, United States | 1983-09-04 | | |
| Glory | Person | Female | Puerto Rico, United States | 1979-02-14 | Puerto Rico, United States | | | 4.5 |
| Gomba Jahbari | Group | | Puerto Rico, United States | | | | | 5 |
| Eddie Gomez | Person | Male | Puerto Rico, United States | 1944-10-04 | San Juan | | | |
| Tito Gómez | Person | Male | Puerto Rico, United States | 1948-04-09 | Juana Díaz | 2007-06-11 | Cali | 5 |
| Nelson González | Person | Male | Puerto Rico, United States | | | | | |
| El Gran Combo de Puerto Rico | Group | | Puerto Rico, United States | 1962-05 | | | | 5 |
| Gran Omar | Person | Male | Puerto Rico, United States | | | | | |
| Anthony del Grosso | Person | Male | | 1986-10-29 | Puerto Rico, United States | | | |
| Guanábanas | Group | | Puerto Rico, United States | | | | | |
| Guaynaa | Person | Male | Puerto Rico, United States | 1992-09-16 | Caguas | | | |
| Paquito Guzmán | Person | Male | Puerto Rico, United States | 1939-11-20 | San Juan | 2021-12-09 | Toa Baja | |
| Héctor el Father | Person | Male | Puerto Rico, United States | 1979-09-04 | Carolina | | | 4 |
| Hednoker | Person | Male | Puerto Rico, United States | | | | | |
| Rafael Hernández Marín | Person | Male | Puerto Rico, United States | 1892-10-24 | Aguadilla | 1965-12-11 | San Juan | |
| César Hernández | Person | Male | Puerto Rico, United States | 1970-10-13 | | | | |
| Giovanni Hidalgo | Person | Male | Puerto Rico, United States | 1963-11-22 | San Juan | | | 5 |
| iLe | Person | Female | Puerto Rico, United States | 1989-04-28 | San Juan | | | |
| India | Person | Female | Puerto Rico, United States | 1969-03-09 | Puerto Rico, United States | | | 4 |